The GCD of given numbers is 43.
Step 1 : Find prime factorization of each number.
$$\begin{aligned}4601 =& 43\cdot107\\[8pt]2021 =& 43\cdot47\\[8pt]\end{aligned}$$(view steps on how to factor 4601 and 2021. )
Step 2 : Put a box around factors that are common for all numbers:
$$\begin{aligned}4601 =& \color{blue}{\boxed{43}}\cdot107\\[8pt]2021 =& \color{blue}{\boxed{43}}\cdot47\\[8pt]\end{aligned}$$Step 3 : Multiply the boxed numbers together:
$$ GCD = 43 $$This solution can be visualized using a Venn diagram.
The GCD equals the product of the numbers at the intersection.